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Nigeria Declares "State Of Emergency" As Study Finds West African Ebola Virus Is Previously Undetected "New Strain"
Following the WHO's warnings, (the ironically named) Nigerian President Goodluck Jonathan has declared a "state of emergency" over the Ebola outbreak that is rapidly escalating in his nation. This comes on the heels of a US medical journal study that finds, as Reuters reports, the Ebola virus that is ravagaing West Africa was not imported from Central Africa but caused by a "new strain" of the disease - raising the specter of further regional epidemics.
Ebola is endemic to Democratic Republic of Congo, Uganda, South Sudan and Gabon, and scientists initially believed that Central Africa's Zaire strain of the virus was responsible for the outbreak. However, as Reuters reports,
Using analysis of blood samples from infected patients, however, researchers determined that while the Guinean form of the Ebola virus (EBOV) showed a 97 percent similarity to the Zaire strain, the disease was not introduced from Central Africa.
"This study demonstrates the emergence of a new EBOV strain in Guinea," wrote the group of more than 30 doctors and scientists, who published their preliminary findings on the website of the New England Journal of Medicine.
...
"It is possible that EBOV has circulated undetected in this region for some time. The emergence of the virus in Guinea highlights the risk of EBOV outbreaks in the whole West African subregion," the report continued.
"What is clear to us from the study is that the virus wasn't brought in from the outside, that it is indigenous," said Tarik Jasarevic, a spokesman for the WHO, which was not involved in authoring the study.
The awful conclusion:
"It means there were possibly outbreaks in the past that were just not detected," he said.
* * *
Nigerian President Jonathan has declared a national state of emergency...
As an example of the concern, banker sin Nigeria are now wearing gloves to serve customers...
* * *
CDC Director Frieden explains his fear about Lagos, Nigeria...
* * *
But President Obama said it would be ok?
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< Don't worry everything is going according to plan.
< Don't worry everything is going according to plan. The plan is Agenda 21 however.
So this explains the sudden VIX Slam / ES Ramp that started at 13:00
BULLISH
fortunately, all americans will be in Health Camps soon. for their own safety.
FEMA camps standing by.
3 billion rounds of ammo.....also standing by. Even the Post Office is ready to go....errr.....postal.
Ebola virus: Nine things to know about the killer disease
The app
http://www.product-reviews.net/2014/07/31/ebola-virus-outbreak-leads-to-...
Going viral
I do agree that it needs to be contained at the source, if it is not be become or be used as the vehicle/weapon for the Great Culling. Hence, contain it IN Africa.
Note also that (a) Nature/Evolution will do what it wants and needs to do, and (b) Ebola is Self-Limiting: like any fire, when it runs out of fuel, it does down. Deal with it. Be PRACTICAL, not a Samaritan Ideologue: do what you have to do, not what you want to do.
Perspective: Let's see this in context of other major causes of death every year: Cancer, Flu, Heart Attack, Stroke, Murders, Car accidents, other Tropical Diseases, HIV/AIDS. Do a PARETO, to help keep perspective. More science & common sense of risk management, and less sensationalism, PR and politics please.
p.s. All major powers and their Big Pharma "friends" (at the 'Umbrella Corporation') can always keep a flotilla of Container Ships a few miles offshore in Africa. That way, they stay local, but at a safe distance, and have all the space and gear they need to do their R & D. Plus a quick way to get more "samples" to observe/test.
pps. If some tens or even hundreds of millions were to die, is that REALLY that "catastrophic" from the global perspective -- given that, as a Species, we are way too successful and have already over-populated the planet? Were it not for modern medicine and technology, there would be half as many people on the planet -- and thus half as many competing for space and resources with each other and with the animal kingdom. Sorry, but I do NOT subscribe to the perverted Christian notion of "having" to "save" or even help the countless masses at the bottom of the food chain. It might be good for bankers (profits), politicians (votes) and clergy (market share), but does not fly with me. When their alleged "Creator" stops being an Absentee Creator/Father/Landlord, then I might consider more obliged to look after these... creatures. And rather than worry about some mythical "Man in the Sky" -- unless he has a fancy and powerful spaceship -- I could not give a crap about such "Fairy tales for adults". Fairy Tales, that are "useful" for the Elite in positions of power. It's just us chickens down here, and there is No Fate, but the one we make. Peddle your snake oil elsewhere.
The Reuters article linked was released back in April. Does this stuff mutate on a dime or what?
That was the original theory, but from what I've read it's been refuted: http://epidemic.bio.ed.ac.uk/ebolavirus_phylogeny
"It seems that removing these intergenic regions results in the Guinea outbreak sequences falling quite firmly within the diversity of Zaire ebolavirus."
http://www.usamriid.army.mil/press_releases/Randy_Final_EID_July_2014.pdf
It gets opportunnities to mutate when it hits patients with multiple viral infections (Ebola + influenza or Ebola + common cold). Right now? Infection base is low. When the number of infected crosses a million you'll probably see some really interesting mutations. [like say Ebola with a 20% mortality (much lower) that spreads like the measles or something weird like that]
Putting it into perspective .... Spanish flu of 1918 had a 3% mortality rate. And it killed 50,000,000 over the course of a couple of years.
Exactly. And this is why ebola getting into Lagos was such a huge fucking deal.
It's out of control now in all kinds of ways.
These people have not been quarantined yet. If it is moderately infectious as it appears, there is no stopping it now.
Fuck! So your saying this thing has 20 million people to practice mutating into the ultimate killing machine?
So did SARS.
Exactly, the threat of mutations is getting closer and closer and when it happens it's another ball game.
mutations don't necessarily = worse. since the goal is living, a succesful mutation could easily mean a less deadly variation so that it can live longer by passing it on to more people.
Not entirely the case. The "most successful" sequence of mutations might be a sequence that prolongs and maximises the infectious phase. So maybe a "better fit" sequence of mutations would see a longer subclinical phase, or at least far milder initial symptoms, with an increased ability for aerosol spread (which has already been demonstrated to occur in the past). Of course, the other "problem" for any pathogen is the Host Response. Too slow a development might allow time for cellular and humoral immunity to develop, so there's the impetus for a faster progression (unless the organism can inhibit the immune response, along the lines of e.g. HIV)
We'll probably see how Ebola adapts to us soon enoough as the case count rises. The inexorable evolutionary advantage of a 3% error rate in transcription per replication cycle means adaptation will occur and with the amplification provided by simple replication, "more successful" progeny will preferentially replicate. For the virus, host death or the ability to mount an effective immune response usually means curtains (although I note a single study indicating that live (i.e. fully infectious) ebola has been recovered from the semen of a male survivor, 42 days post infection . . . .), so maybe we'll see the development of a "persistent" carrier state amongst survivors - an "Ebola Typhoid Mary" scenario.
All hypothesis of course, but interesting for those of us "in the business".
You mean barbed wire surrounded Fusion Detention Centers with guard towers staffed by former TSA agents, unemployed at their airport security jobs after most air traffic was grounded to prevent the spread of Ebola virus.
Don't be silly, they'd get paid leave indefinitely.
I am not sure if I have Ebola or if it was just the Hot Pocket I had last night.
pods
What do you think gives the pink slime inside your Hot Pocket that pink color ?
bush meat burger and fruit bat dessert please
well, did you die and re-incarnate as a root beer dispenser, or a cherry slurpee machine?
Did ya ever catch toilet paper on fire?
HaaaaaaaT Pock-et.
pods
L.A. Beast ain't scared.
https://www.youtube.com/watch?v=uDyADA9RX1U
Ahhh, the rise of "competitive eating."
pods
LOL !!
+1000 Revelations
Government always needs to remind us why we "need" it
Is that you, Jim Gaffigan?
You gonna eat that or do you want me to just throw it against the back of the toilet for you now?
pods
"What are you gonna shit? HOT POCKET!"
Death Pockets!!
Have you tried the hot pocket, hot pocket....it's a hot pocket stuffed with a hot pocket.
What did these clowns take the exact same script as "OUTBREAK". Geez no originality whatso ever
New strain? Never would have guessed.
I guess the fact that it's fucking AIRBORNE should have been a god-damned clue to these folks.
Let's call it ... Ebola Motaba
Spine or Miffed (hell any ZH doctor's opinion solicited) .... your thoughts on this one?
Worst case:
Imagine an Ebola + Influenza patient later this winter. They're most likely dead men/women walking but perfect breeding grounds for BILLIONS of interactions between ebola and the flu. And this could happen to thousands of people. Results?
Ebola virus with a much hardier protein coat. / Flu virus that induces hemorrhagic fever symptoms
Or .... Ebola + Rhinovirus.
Ebola that is as contagious as the common cold. With as many variants.
Or how about??
•Hemorrhagic Herpes
•Hemorrhagic Chlaymidia
•Hemorrhagic Measles
Now before ANYONE says "Oh this shit will never happen" .... some thoughts
•In any given infected patient there are billions (10^9) of virii of potentially different types.
•Thousands of people infected : Quadrillions of interactions (10^12 interactions)
•Millions of people infected: Quintillions of interactions (10^15 interactions)
Sure the odds could get ultra remote, but with that many interactions statistically it becomes likely.
How RNA viruses exchange their genetic material
•http://www.ncbi.nlm.nih.gov/pubmed/11732610
Chapter 43Viral Genetics
•http://www.ncbi.nlm.nih.gov/books/NBK8439/
Recombination
Recombination involves the exchange of genetic material between two related viruses during coinfection of a host cell.
Recombination of Viral Genome
•http://www.hhmi.org/biointeractive/recombination-viral-genome
When two different strains of influenza infect a single cell, their genetic material can mix freely, resulting in a new third strain of influenza.
Box 3 | Recombination and viral emergence
•http://www.nature.com/nrmicro/journal/v9/n8/box/nrmicro2614_BX3.html
For most RNA viruses, cross-species transmission is the most common way for a virus to enter a new host. Recombination could assist in this process because it enables viruses to explore a greater proportion of the sequence space than is accessible by mutation at any one time, thereby increasing the likelihood of finding a genetic configuration that facilitates host adaptation. Notably, many recently emerged human diseases are caused by RNA viruses that display active recombination or reassortment.
RNA viral types
Same Order
•Filoviruses - Ebola, Marburg
•Rhabdoviridae - Rabies
•Paramyxoviridae—includes Measles virus, Mumps virus, Nipah virus, Hendra virus
Same Group : Group V—negative-sense ssRNA viruses [all of the above]
Orthomyxoviridae—includes Influenza viruses
•Hanta virus
•Lassa virus
Other RNA types
•Rota virus - Nearly every child in the world has been infected with rotavirus at least once by the age of five
•Picornaviridae—includes Poliovirus, the common cold virus (Rhinovirus), Hepatitis A virus
New strain? US Military Bio-Lab in West Africa:
http://www.economicpolicyjournal.com/2014/08/the-us-military-and-ebola-o...
"The Last Gasp" Great book. Was somewhat dated until about a month ago. About a buck on Amazon.
"The Cobra Event"
The death scene in the opening chapter of this book is as scary a thing as I have ever read from any horror novel. But it's based on real symptoms.
http://www.amazon.com/The-Cobra-Event-Richard-Preston/dp/0679457143/ref=...
I picked that book up about a week ago. Now I feel like I am seeing the movie first. May read it anyway this weekend.
THey new it was a new strain in April (or before): http://www.cidrap.umn.edu/news-perspective/2014/04/study-growing-guinea-...
Then theres the problem of having a "vaccine: waiting in the wings. Vaccines arent buckshots. Cant jus hit a bunch. It has to be targeted to work. If its a "new" strain and "new" vaccine, MAPP Pharma is really, really fast.
This is a realease, either intentionally or inadvertently.
One of their researchers was interviewed on BBC radio today. He stated very clearly that they had been working on vaccine for `Weaponised Ebola`....or what they thought a weaponised Ebola might be like,`just in case`. They were not working on one for any of the documented strains of Ebola already known to exist in the wild. He said also that this is why confidence that it will work can not be 100%, but said that for patients with a choice between giving it a go or taking their chances with Ebola it was an easy descision. This is a TINY company, less than 10 employees, the interviewer said they had been unable to talk to the CEO `who seems very elusive`
I wonder if the researcher said a bit too much in the way of fact by mistake?
Sounds fishy to me.
There are no (that I am aware of) efforts to weaponized virus. It's too hard and there are no battlefield uses for it. There are easier ways to deliver a virus to a civilian population than trying to put it into a weapon. Like, sleeze into a water treatment plant and add it into an injector, or spray it around at an one-air market, or a school ground.
So nothing the guy says makes any sense.
Also the government would not work with a 10-man company working on a treatment for some mythical "weaponized" ebola; you have to be deep into the M/IC already to get a contract like that. And if you do get the contract you don't talk about it ever to anyone. You do, your contract is pulled and just maybe you have "an accident" shortly after.
Probably the guy is a fake, or if not then is just talking up his company stock, or something.
Actually in March they proved that it was in the MRU at least as far back as 2006 (the oldest Lassa test specimens on hand).
Serious question here...I have a really hard time believing this is some grand plan to kill a billion people. If I was an elite, ultra power guy, with dreams of getting the population down to 500 million, why mess around with the optics? If I was hell bent on this plan, why take the chance of releasing my pathogen in the shithole of africa? What if it actually ends up being contained...then what? Why the show? If you are going to kill billions of people why would you really care "how it looks"? Why not go for the gold and release in NYC and blame ISIS?
And even then, a virus like this does have the kill rate to accomplish the stated goal. No, this is just nature fucking with us. Again.
To your thought experiment about a big wig sociopath wanting to cull the herd, I wonder what would even be the point of the effort? They don't really care how many people there are in the world. Power resides at the top, moves around in the top, and stays in the top. If you are already at the top you know all this and frankly do not care what happens below the top. The rest of us down here like to think the guys up there care about us even enough to kill us, but they just don't.
We simply do not exist except maybe as consumers, and then only in the aggregate as targets for marketing and propaganda, and then only if we have disposable income.
Lost Word
Yes indeed,
US Bio-warfare researchers are there
The research program, occurring in Sierra Leone, the Republic of Guinea, and Liberia—said to be the epicenter of the 2014 Ebola outbreak—has the announced purpose, among others, of detecting the future use of fever-viruses as bioweapons.
http://www.globalresearch.ca/what-are-us-biological-warfare-researchers-...
If it were completely airborne wouldn't the infection rate be FAR higher than it is? However, perhaps it's airborne on a low-level, explaining how all the health workers in close contact with the infection, yet wearing all the protective clothing and gear, have come down with it. There's definitely something different going on.
There's airborne and airborne .... fomites and droplets. Look up the R Naught (R0) term and it can help understand the spread of an epidemic.
Also here are some values I collected. [And yes I freely admit that I have done a LOT of crash course reading on microbiology in the last week. ]
Values of R0 of well-known infectious diseases
Disease Transmission R0
Measles Airborne 12–18
Pertussis Airborne droplet 12–17
Diphtheria Saliva 6–7
Smallpox Airborne droplet 5–7
Polio Fecal-oral route 5–7
Rubella Airborne droplet 5–7
Mumps Airborne droplet 4–7
HIV/AIDS Sexual contact 2–5
SARS Airborne droplet 2–5
Influenza(1918) Airborne droplet 2–3
Ebola *old* Bodily Fluids 1–4
Ebola *2014* Airborne Droplet (???) ???
Watched the movie Contagion last night and supposedly that one was a flu with encephalitis symptoms and a 25-30% mortality rate with an R0 of 2 in the first wave. Then it jumped up after it did some recombination in a cluster. Then it REALLY got going.
Cool info. A couple years ago I caught pertussis -- I know exactly where it came from -- a hacking couple near me on an Amtrak train. I had a recent DPT booster so that failed completely. At first they just diagnosed my case as flu or some respiratory infection, gave me a "Z pack" of antibiotics and sent me on my way. Of course, at this time I was at my most contagious to others. As time went on it morphed into the most wretched cough one can imagine. Lasted for weeks. Finally my doctor admitted that pertussis (whooping cough) is all over the place but isn't officially tracked by CDC nor do they like even like officially recording it onto their computer files (my HMO, not the CDC). To this day my record just indicates "flu"-like symptoms.
So I understand now how that R0 works. Imagine genetically piggy-backing some other virus onto the pertussis chain?
I highly recommend this website for anyone who wants to understand virus evolution and current epidemic threats http://www.recombinomics.com/ .
Without testing you really don't know. Your symptoms sounds more like mycoplasma to me. They can test but it's expensive to do the PCR so they always blow people off. I run my sample off line at work on an array to diagnose myself. Advantages being on the inside.
Miffed;-)
If I had to hazard a guess, I think a new semi-airborne strain of ebola has probably risen on that scale to around that of SARS or maybe smallpox.
So, not very high.
I say this because we're seeing some alarming spread, but nothing like the common cold or influenza. Influenza is deadly not because it is highly lethal, but because everyone (I mean everyone) gets it when it shows up. It just spreads like a nasty rumour, jumping easily across an entire community overnight (meaning 24 literal hours). Since everyone gets it, and there are lots of people on the border of ill-health anyway, it really burns through the community killing anyone cannot endure the symptoms.
Now, if ebola ever becomes as transmissible as say measles -- and if the latency with infection is at least 10 days up to 30, almost what we are seeing -- we'd have a fight on our hands. A serious fight, one for the ages. Even with a fairly narrow ability to spread this thing is so lethal that the impacts would be horrendous and enduring.
It goes with my hemorrhagic wallet.
Better known as the Ham Wallet for most of the month.
pods
Is that like a Wish sandwich?
More like a:
http://www.urbandictionary.com/define.php?term=fish%20mitten
I see what you did there...
I learn somethng new every day.
<chuckling ruefully.....shaking head> So do I.
What would REALLY suck is if Ebola hooked up with the Marburg virus and had a litter load of kids.
That would SERIOUSLY crimp the neighborhood.
I don't think viruses breed. They're like politicians; they reproduce by stealing someone else's reproductive capacity, then forcing it to spew out mini-mes.
Understood.......but nothing stops these two virri from hooking up in some pig's or monkey's gut.....exchanging phone numbers.....and then some native eats said pig or monkey with the new and improved offspring.
Dante's Inferno was not Hell.......it's inside the gut of some tasty bush meat down in "Jungleland"
https://www.youtube.com/watch?v=JR_0nbEzVdY
What you describe is very much what happens when a "swine flu" or "bird flu" learns how to infect humans. It's random, but well understood. And it's why these nasties always seem to come from Africa or Asia where people still live in very close (sometimes, unhygienic) proximity to animals.
With industrialized farming here in the states.....it could happen here.
I don't know if you ever watched "Millineum" back in the 90's. It was a series created by Chris Carter of the X-Files which dealt with the rise of serial killings and general end-times hysteria leading up to the year 2000.
There was a story arc begun in the second season where a splinter group of ex-FBI and intelligence folks known as the Millineum Group who on the surface seemed to be helping the hero Frank Black solve crimes actually were engineering a variant of the Marburg virus in order to bring about a cull of the population in order for them to attain power and re-make the world into a more peaceful place.
The last episode of Season Two is one of the most chilling things ever shown on network television. Particularly in the way that it was shot. If you are a fan or know something about the show....you realize that most of the scenes are shot very dark with subdued, almost monocromatic colors. Like in the movie Seven....which Chris Carter said inspired him for the making of Millineum.
But this last episode.....the death scenes of the chicken farmer.....and later the family cooking out.....were all brightly lit and cheerful. And there was no music. Usually there was always some forlorn and sorrowful soundtrack playing in the background of a typical Millineum scene. Not these scenes. It only heightened the horror of what went down in these scenes.
Check it out. As wth life.....soemtimes the scariest monster of all is not the monster.....or even the human boogy-man. In the words of that Bush song...."it's the little things that kill"
At least the Russians are there to decipher what's going on.
No other country has sent any top scientists, not that I have heard of....what's with the US Govt and EU/UK Govt helping people they send money to and host dinner parties for?
Moscow scientist: There has been a turning point in battle against Ebola August 8, 2014 Gleb Fedorov, RBTH Although the number of people infected with Ebola fever in West Africa continues to grow and it is nearly impossible to control the spread of the virus, in recent days it has been possible to improve the situation, a leading Russian expert in virology told RBTH in an interview.
Source: Russia Beyond the Headlines - http://rbth.com/society/2014/08/08/moscow_scientist_there_has_been_a_turning_point_in_battle_against_ebo_38869.html)
That article states that there has been cases in Nigeria and Hong Kong. No mention of the Hong Kong case in the media.
FTA:
RBTH: In your opinion, how can the epidemic be stopped?
Shchelkanov: This is complicated for two fundamental reasons.
First, the infection is zoonotic [meaning it can be passed between animals and humans]. It’s virtually impossible to control the circulation of viruses in hot spots in the wooded [countries of] Guinea, Sierra Leone and Liberia.
The second fundamental reason lies in the socioeconomic conditions of these countries. West Africa is one of the poorest territories [in the world]. There are no sanitary and epidemiological services as we know them.
OK, so who's going to show up for work if they have a fever of 106oF and they're puking and shitting their brains out? What happens to the vaunted US sanitation system? What happens to the electrical grid? Hell, what happens to the spent fuel ponds at the nuclear reactor next door?
Something tells me conditions in the US, or any developed country, could quickly regress to something less advanced.Bingo.
Watch this for a theatrical illustration of a worst-case scenario: https://www.youtube.com/watch?v=Eym4PwHmUvI#t=11
Dubaibanker, you remind me of the good quality stuff the blogger formerly known as "Bank Guy from Brussels" used to post. Till he (was) vanished from ZH.
i was thinking the same thing, Kirk...most of the fuss was centered on good ole francis sawyer, but janus was mighty-sore over the loss of 'bank guy from brussels'...i really, really miss that guy -- but i'd more than welcome the return of a reasonable facsimile.
one other thing:
WHERE THE FUCK ARE THOSE TEST RESULTS OUTTA MT. SINAI IN NYC?
something rotten this way wafts, and i don't like it one bit.
we've got the entire news-media/press-corps clustered in that one city, and none of them has the stones to demand test-results? lots & lots & lots of people are going to pay for this shit. members of 'media', do you really think you'll be 'immune' from the scourging that awaiteth power? oh, my poor-poor dears, you'll be turned into human effigies, into living symbols of the perfidy surrounding us all...you filthy swine in 'media' are only fit for the slaughter.
media, here's a catchy and alliterative headline from the future:
"Former Media Mavens Mauled Into Mincemeat By Angry Mobs"
and now, the blurb beneath it
'hundreds of thousands turned out to see a parade of pundits executed at high-noon. then the festivities assumed a more jubilant hue as the pressers were hacked to bits and their remains strewn over rolling pastures, where a delighted flock of buzzards and other carrion-fowl had a field day with their guts and picked their bones to a gleaming white.'
now that's a story i'd pay to read!
get me some test results, cunts!
https://www.youtube.com/watch?v=Jeg-jT7MnEs
so don't play with me/
cause you're playing with fire,
janus
Yesterday's news. Negative. Of course.
okay, well, after a few minutes of googling, it seems the negative results were released (but to very little fanfare)...nevertheless, i'm going to let my statement above stand, as i'm absolutely disgusted with press coverage on this (and every other) issue.
ZHealots, we're now so far into bizzaro-world that we've staked out a policy of shutting off the flow of hydrocarbons to europe from russia while at the same time opening the spigot of ebola from africa to america.
congrats on your demonocracy, amorica...and hip-hip for all her noble institutions. the movie 'idiocracy' is starting to look like an optimistic aspiration...don't fret, though -- just take a few 'mood-stablizers' and tune into the boob-tube.
have a pleasant and ebola-free weekend, bitchez...,
janus
Thanks, Captain Kirk! I am glad someone reads and appreciates the comments I write.
you actually hit on one point i made to some knucklehead on facebook the other day.
the timing of this outbreak could not be worse. you have millions of people returning to school packed into classrooms and dorms, some of which are arriving from all over the world. perfect way to spread any virus.
and on top of that the cold and flu season is right around the corner. someone who has ebola may think they have the common cold or the flu and by the time they realize something is really wrong they will have spread ebola all over the place.
another thing to think about is if someone has a cold or flu and get exposed to ebola their immune system wont be able to handle the double whammy and mortality rates will skyrocket. when we start having those deaths the panic will REALLY set in.
Thanks SilverRhino ! You know just how to brighten my day !
I don't even know where to begin... But let me try...
To get mixing and matching of phenotypic traits between two viruses, you need exchange of genetic material.
1. Chlamydia is not even a virus so there is zero chance of gene transfer between it and any eukaryotic virus.
2. Herpesviruses are DNA viruses. You would need virtually a mathematically impossible set of enzymes and conditions for a DNA virus to exchange genetic material with a purely RNA virus in a single host cell. Just to give you an idea, herpes simplex virus replicates its genome in the nucleus while Ebola virus replicates its genome in the cytoplasm. In case of a co-infection, there is close to zero chance for the two genomes to interact with one another in the cell. This is just one example, there are plenty of other necessary conditions required for genetic exchange, one of which I will highlight below.
3. One of the special things about influenza genome replication is that, unlike virtually all RNA viruses, it happens in the host nucleus. So sorry to disappoint you... there you go, genomes of Ebola virus and flu do not interact in the cell.
4. The most efficient method for two viruses with non-segmented genomes to exchange genes is by recombination, and because the most common enzymes for recombination target DNA molecules, the most frequent type of recombination happens between two DNA viruses (or a RNA virus with DNA phase, like HIV). Ebola virus has a negative sense RNA genome, it cannot recombine with a DNA genome, and is highly unlikely to recombine with a positive sense genome (e.g. SARS, MERS). The Ebola virus genome, once produced, is coated with its nucleoprotein to shield it from recognition by the host sensing molecules (RIG-I). The Ebola genome is thus only exposed for a very brief period of time (probably microseconds), and exposure is a necessary condition required for interaction and recombination with another genome.
5. Recombination of two negative sense RNA genomes resulting in a viable virus has also never been observed in vitro and in nature.
6. At the population level, humans and animals already do get co-infected with two viruses all the time. For example, HIV patients are immunocompromised, so they often get co-infected by other viruses and bacteria. If what you propose happens that easily, by now we would have seen at least a few mutant RNA viruses which have mixed genomes from different families. And we do not see that.
Yep, sure sounds like everything is under control.
I am prone to the concept of malaria. Ebola transmitted by mosquitos.
Interesting thing about malaria. Sickle-cell trait provides an immunity to malaria. Sickle-cell developed in Africa where malaria is endemic. It is helpful there. Not so in places where there IS no malaria around, though. So, sickle cell becomes a problem when those Africans leave that area, and go where there IS no malaria. Then it confers no benefit, only illness.
Humans and infectious organisms can and do adjust to one another on the local level. We make things much worse by our constant traveling all over the place. And globalization will bring us many more such problems.
Kevin Henry eats Ebola for breakfast.
Hat tip to Kevin today.
Evolution? What's that?
It's what stops when you don't clean the gene pool.
It's all Obama's fault.
"The new strain"
Yeah...the African that brought it to Nigeria was literally urinating on the people trying to help him in order to purposefully infect them. I'm not going to cite, research it yourself.
The virus was working on his brain by that point.
yeah, it's a virus that causes savage behaviour in savages. Not their culture, or their DNA.
As soon as he's healed up, he's going to start his new career in edumacashun and NASA an gettin his life straight, right?
He died.
insane in the membrane.
they also talk about how the face looks at the end but no one ever posts pictures. Could it resemble Liza Minelli's or Joan Rivers?
Exactly. The virus isn't suddently airborn or things like that. It just so happen that some patients that got it are acting Extremely stupid!
The guy name is Patrick Sawyer. Her sister had ebola, he was seen with her blood on his clothes but he never though he could be infected! Genius. Then he goes to an hospital to ask whats wrong with him, and then tell him he have ebola. He won't beleive it and start urinating of the hospital personnel. Genius again!
Not sure exactly when exactly he traveled to nigerian in that story, but he already knew he had it when he did, but he wanted to go to a conference anyway.
This type of behavior is why the virus is spreading so much right now. Simple stupidity.
Portuguese MO for screening inbound passengers:
Hello Sir, mind if I ask you a few questions, don't worry ,won't take long.
Have you had a fever in the past 48 hours? No? Good.
Is your head aching? Joints? Bones? Anything? No? Good.
Have you had any spontaneous bleeding episode recently? No, of course ,not, there's a good lad.
Are you in contact, sporadic or steadily maintained, with people known to have been affected by hemorrhagic viral disease? Okay, it's just a standard question. Thank you.
There you go, enjoy your stay, hope to see you soon Sir thank you, best.
We deserve it.
Hopefully they remember to shake the inbound's hand, or give them two or three cheek bumps in welcome.
We knew this over a month ago.
Yeah, back in April.
http://epidemic.bio.ed.ac.uk/ebolavirus_phylogeny
"One finding of this is that the 2014 sequences fall as a divergent lineage outside the Zaire lineage suggesting that this may be a pre-existing endemic virus in West Africa rather than the result of spread of the EBOV lineage from the Central African countries that have had previous human outbreaks."
Word of this was known before it was published, and the nutters went fill tinfoil upon the return of the doctors to the US...
http://www.usamriid.army.mil/press_releases/Randy_Final_EID_July_2014.pdf
I read the virus can be detected in semen up to 7 weeks after a man recovers. There's no way this is going to be easily contained.
Especially if it makes it to the red light district in Singapore or Hong Kong.
....or the White House.
Explains alot the White House having a red light district. Easier for the Secret Service
if it makes it to the white house that will really only affect the gay population around DC.
Which means all of those Chinese customers will bring it back to their wives on the mainland.
LoP...add any sizeable city to that list...Jakarta, Bangkok. Delhi, Mumbai, Kalkuta, Yangroon, HCM, Manila, Seoul, etc. the list will be as exponential as the mathematical spread. 5-6 million dead 12 months from now.
This graph is just getting started.....
Bangcock, Oriental city
but the city don't KNOW
what the city is gettin!
Shit that Murray Head sanz, or something
This is going to go through the gay community like gasoline rain on a fire.
Remember the story of the Saudi who traveled over there for business and contracted the disease but only found out about it after he got home ?
I bet his pecker picked it up and kept a little sumpin' sumpin' for itself.
I can do just so much fear, Tylers.
Full Metal Bitch: "Maybe we should just reset."
i will have a single serving of ebola with my fukashima fish sandwhich. put me down for a dashiki too please. i want to look sharp while my fucking organs are melting out of my ass.
ROFL!
Well here ya go... http://www.youtube.com/watch?v=Gs069dndIYk
+1000 Perfect !
Not to worry.
Warren Buffet, Bill Gates, Ted Turner with a generous philanthropic endowment from David Rockefeller and David Mayer Rothchild got it covered.
They've been working on this one night and day so you won't have to!!!!
http://www.smartsurvivalkits.com/product/survival-kits/pandemic-kits/sta...
get one now before it goes airborne!!!!
NOW, how do you safely get out of it?
I suppose you could spray yourself down with Everclear, then burn the runoff.
That sounds like a Pandemic Facebook Challenge.
I'll stick with my full face respirator with P100 cartridges and a case of Saranex suits.
Tyvex, goggles and a dust mask is so Y2K.
I've got my bunny suit.
https://4.bp.blogspot.com/-lFnGNKMO1ko/Ugyvna9a8-I/AAAAAAABG5U/sre1374oV...
Please do that. And how do you change out of said suit and respirator at the end of the day? Do you have a clean room? And after you change, how do you dispose of said gear?
Good luck with that. There is no way you can hope to buy shit off Amazon and exepect it to save you.
And if you make it past the first wave, expect another every 6-12 months. EBV can infect other mammals even if it is not deadly. Mosquitos and other vectors will be a problem.
Then there's the food chain...
Good luck. If you can't develop natural antibodies or get them from somewhere else you will only be living on borrowed time.
You convert your shed into a chemical shower room. Here's the protocol:
1. Return home after a busy day of looting for canned food at the local abandoned Walmart.
2. Step into the modified shed. Shower with diluted bleach for a few minutes.
3. Turn off the shower and stand there waiting for a few more minutes for the bleach to kill all the remaining microbes.
4. Step into a large tub of bleach, remove the Saranex suit and let it drop into the tub. Do the same for any underwear you are wearing. Let them soak in the chemical tub for another round of sterilization. Place the respirator on the side (they are not waterproof), and let it sit under the sun for hours (yes, dessication works quite well for an enveloped virus like Ebola).
5. You should be naked by now. Take the shortest path to the nearest water tap and take a bath, using large amounts of soap (not the mild type). Make sure the soap covers every part of your body.
6. Rinse all gear with water and dry them. Just for good measure, wipe down the respirator with some bleach.
7. You and your gear are ready to go back into the Ebola-infested world again.
:)
If you are intentionally going to contact Ebola, you really should be working in protective gear up to BSL 4 standards, which requires positive pressure in the suit with independant environmental filtering.
The best thing to do would be quarentine your group from the general population completely for as long as practicible.
The best thing to do is not to travel to Ebola infested Africa
Then vote for politicians who will not allow infected Ebola patients from coming to this country.
And if they do.....you need to run the politcian out of town....forcefully if necessary.
If you're that scared to go the lengths you guys describe above....it's time for you to pick up the gun and take over the government by force.
Otherwise.....wash your hands diligently.....be suspicious of people you haven't seen before with an African accent or who state to you they have been to Africa lately....and limit your contact with them. And if they get offended....tough shit. Tell them you'll apologize to them in 6 months if you see them again.
Goodluck, Jonathan
OH Lets catch up its mutating, LOL "The STRAIN"
right now im rooting for Putin, and the uncle on "TYRANT""
no border problem, no ID theft....its time ...
Cough now, cough up blood later.
How's about a cross reference with the local bio-weapons lab over in Liberia or wherever....Soros? You wanna field this one?
...Caling Kevin Bacon calling Kevin Bacon....I think it is time to drop that HUGE Fuel-Air Mixture bomb as advertised in "Outbreak" with Cuba Gooding jr in the pilot's seat. Maybe several. USAF has them stashed al over the globe. Like Diego Garcia, a short hop.
They won't know what hit them. Cripsy critters. It'll give good biz to Caterpillar, bringing in earthmoving equipment to scrape Lagos off the map.
Long Caterpillar bitchez!
Why don't they have an F'n strain for bankers.
Shouldn't take more than US$500m of aid for the problem to disappear! Just send the cash & we will 'take it' from there!
A goalpost shifting virus. How very unsporting (& G-S) of it.
What is needed is a virus with a morality
if it kills everyone in the white house and on capital hill it will be the most moral organism on the planet.
too much nigerians in US in banking... that isn't a problem until now.
go ebo, go
the summum of hilarity whould be a bunch of cali faggots getting ebola, then go in their fist fuck - suck party.
3 weeks later, 1 million cali faggot less on the ground, housing rent lowering by 40% since google lost employees..
HELL OH HELL
Wear gloves to protect from ebola.
Rub eyes while wearing gloves.
...international air travel WILL cease, not by any gov't decree, but by folks simply canceling their suddenly unimportant flight plans.
Short the airlines stock, no need to do this from WTC buildings 1 & 2.
Ooops, they got disappeared?
I wonder how aspirin, now that it helps cancer, Interacts with Ebola.
Keeps the clotting down so it's over quicker.
Markets LOVE IT...buy buy buy
President Goodluck Jonathan and Vice President Goodnight Irene.
When you take your gloves off, one hand does not touch the outside of the other glove but the other hand does touch the outside of the glove. Think about it.
"New Strain" this confirms the worst fear. Evolution has changed the virus and made it easier to spread. If it makes another genetic mutation to favor spread through the airborne route, then all hell descends on us. Africans will be flying into Western Airports all over Europe, Canada, USA, Australia and New Zealand. Wherever the culture is European and white, theis is where they will flee to. And we know why of course, because we are the only people who will risk ourselves and drop everything to care for them. All the while the liberals will bash Whites for being evil racists. A liberal can't open his mouth without hate for whites coming out of it. Sorry is that offends some people, but why do blacks run to white society whenever they can scare up the airfare, or boat passage?
Pssst - your avatar is a clue...
Needs a bigger ass
Yours is JUST fine.
I mean....your avatar's.
<sheesh...ok, shutting up now>
That is some seriously well-appointed bunghole.
mmmpphhh !
< fingers tracing zipping motion across lips >
She is now a year older than when she first hit the midea spotlight, this girl is over thirty and just looks better with an added year. Not that I will ever see action like that again. Too old!
Passing Answers: 82% to 100% grade - "the Tyranny of Poverty"
72% to 81% grade - "R I F, Reading is FUN"
Governments need to close their boarders to people (black. brown, yellow, white, purple with orange stripes) arriving from affected areas until the crisis has passed.
The majority of airlines are still putting profit before the safety of their passengers, therefore Governments need to impose travel bans on them.
they will flee to western countries looking for that experimental serum they've been hearing about.
They will fly in in the perfect knowledge that by arriving, they will be taken to the finest medial centers on earth and no expense will be spared. IF, a person in one of these countires suspects they may have had contact with Ebola, and they had the money for a ticket, it makes all sense for them to fly to the United Kingdom and rent a room until they either get sick or are sure they are virus free. If they get ill, they are assured free and unlimited care of the highest kind. This action would be plain common sense for those who can afford it. That is why I say, that many with the fear of infection will race to fly to any first world nation. Canada for example, free health care, UK free health care, Sweden free health care. I swear that ebloa tourists will start making the trip, and governments and airlines will do nothing to stop them.
Well, there IS a spot of good news there. Viruses tend to mutate more when they are jumping species, as Ebola has been doing. But most of the mutations will result in lesser virulence over time, as the virus adjusts to its new host. It's those first meetings that tend to be ugly.
The ideal situation for a virus is a host that will allow it a place to replicate, and spread. The replication is no problem for Ebola, but the spreading part is problematic when you are killing your host off so quickly. If the host dies before the virus can jump to someone else, it's a dead-end for that virus.
But it takes time, and mutation, for a new virus to make the adjustments needed to merely sicken the host rather than kill it. Better still if you can persuade the host to allow you to set up housekeeping, like the virus that gives you chicken pox, that afterwards goes to live in your nerves, where it usually behaves itself. (though some DO get shingles...still, not usually fatal) And many viruses have even gone as far as to provide some benefits to their hosts.
Viruses don't 'want' to kill us. They NEED us. It's just a matter of negotiating the terms. Airborne transmission IS scary, but is also likely to result in a 'tamer' Ebola that just slaps you around a little instead of turning you to soup in a skin bag.
I just went through the entire 5 pages of the previous Nigerian blog and this one.. There was one small section with the mention of Silver ions/colloidal silver/cs in the previous blog. Nothing in this blog It was dismissed as not possible for this "medicine" to cure Ebola. Also that there was no clinical study. I am attaching a link to a "supposed declassified DOD clinical study" and this link is the PowerPoint (???) presentation.
http://thesilveredge.com/study-defense-threat-reduction-agency-silver-nanoparticles-neutralize-hemorrhagic-fever-viruses.shtml
The link opens a PDF file
I am not a microbiologist nor a medical person. Is this presentation legit?? If legit, does it have merit as a possible cure/preventative. Who can help explain this presentation?
Duh, let me take a wild stab at this.
The people marketing colliodal silver?
cannot up arrow you due to the italics, but all I'm sayin is you must be related to that Occam guy.
May I give this guy a plug? I use his zappers & colloidal silver kit http://www.orgoniseafrica.com/colloidal-silver-kit.html#.U-URrOz5Zdg
No connection other than being a happy, illness-free customer.
His site is well worth a read. (The 'Orgonite' bit may be too much for some souls though. Depends perhaps on why you think you are on this planet?)