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NYC Ebola Patient's Condition Worsens As Fiancee Returns Home
New York City health officials have released Morgan Dixon, the 30-year-old fiancée of recently diagnosed Ebola patient Dr. Craig Spencer, to her West 147th Street Manhattan apartment where, as WSJ reports, she will remain under mandatory quarantine. This 'good' news comes as New York's Department of Health issues a statement on the deteriorating condition of Dr. Spencer who "is entering the next phase of the illness, which is anticipated gastrointestinal symptoms." This was expected apparently, as NYC's health commissioner Mary Basset noted, "we've seen with this disease that it continues to get worse before it gets better." A large CDC team is actively involved.
Wearing a scarf and coat, Morgan Dixon the fiancée of NYC doc with Ebola just returned to their apt for quarantine. pic.twitter.com/5L7QGFU0eI
— Don Champion (@DonChampionTV) October 25, 2014
The good news... (via WSJ)
New York City health officials were preparing Saturday to release the fiancée of a recently diagnosed Ebola patient to her Manhattan apartment where she will remain under quarantine.
Morgan Dixon, 30 years old, was in close contact with Dr. Craig Spencer since he returned to his New York City home on Oct. 17 from treating Ebola patients in Guinea, officials said, and had been with her fiancé at Bellevue Hospital Center since he was diagnosed with the virus on Thursday.
Ms. Dixon was free to leave the hospital Saturday, according to Dr. Bassett. She had no symptoms and had been admitted out of caution, the health commissioner said.
Dr. Bassett said she was confident the city had tracked down everyone that Dr. Spencer had come into contact with.
The bad news...Dr. Spencer's condition deteriorates...
Ebola patient entering next phase of illness, which is anticipated gastrointestinal symptoms, according to joint statement from Health and Hospitals Corp., Department of Health and Mental Hygiene.
Patient is awake and communicating
Bellevue clinical team is in constant communication with CDC and other leading medical centers such as Emory University Hospital and Nebraska Medical Center
Large CDC team has been advising Bellevue staff
In addition to required supportive therapy, Bellevue initiated antiviral therapy within hours of admission; also administered plasma therapy yesterday; these therapies have been used at Emory and Nebraska
"We've seen with this disease that it continues to get worse before it gets better," Dr. Bassett said.
*NY EBOLA PATIENT RECEIVED CHIMERIX'S BRINCIDOFOVIR (the same drug that did not work for Thomas Duncan in Dallas)
As NY Times reports,
The statement was careful not to convey a sense of pessimism, and patients undergoing treatment can worsen before they recover. In a brief telephone interview from his room at Bellevue, Dr. Spencer spoke in a neutral tone that seemed stripped of illusions: “I’m still undergoing treatment,” he said.
* * *
Joint Statement of Health and Hospitals Corporation and Department of Health and Mental Hygiene
The patient at Bellevue Hospital Center is entering the next phase of his illness, as anticipated with the appearance of gastrointestinal symptoms.
The patient is awake and communicating. The Bellevue clinical team in charge of care for the patient is in constant communication with CDC and with other leading medical centers such as Emory University Hospital and the Nebraska Medical Center. A large CDC team has been actively involved in advising the Bellevue staff and we are very appreciative of the additional guidance.
In addition to the required supportive therapy, we initiated antiviral therapy within hours of admission. We also administered plasma therapy yesterday. These therapies have been used at Emory and Nebraska.
The patient's fiancée will return to her home this evening under quarantine.
* * *
The full timeline of Dr. Spencer's time since arrival, in NYC...
On 10/14, the patient departed Guinea on a flight to Brussels. Patient reported no symptoms.
On 10/17, the patient boarded a flight to the U.S. on Brussels Airlines Flight SN0501. Patient reported no symptoms.
On 10/17, the patient arrived at JFK. The patient was screened at JFK and had no symptoms upon arrival.
On 10/21 at 7 AM, the patient reported fatigue and exhaustion. No fever, vomiting, diarrhea. Fatigue is a symptom of Ebola, but it is very unlikely that people he came into close contact with on 10/21 are at risk. Out of an abundance of caution, we are actively monitoring the health of these close contacts.
On 10/21, around 3:00 PM, the patient visited The Meatball Shop. The Meatball Shop is located at 64 Greenwich Avenue. Spent 40 minutes at The Meatball Shop.
On 10/21, around 4:30 PM, the patient visited the High Line. Walked on High Line and stopped at the Blue Bottle Coffee stand (10th Ave & W 16th St)
On 10/21, around 5:30 PM, the patient got off the High Line at 34th Street and took the 1 train to the 145th Street station.
On 10/22, around 1:00 PM, the patient went running along Riverside Drive and Westside Highway
On 10/22, around 2:00 PM, the patient went to pick up Community Supported Agriculture (CSA) farm share at 143rd St and Amsterdam Avenue (Corbin Hill Farm) Patient picked up box and brought back to apartment
On 10/22, around 5:30 PM, the patient left for The Gutter bowling alley in Williamsburg, Brooklyn with two friends. For his arrival at Gutter, the patient took the A train at 145th Street and transferred at 14th Street and took the L train to Bedford Avenue.
On 10/22, around 8:30 PM, the patient left The Gutter. For his return trip, the patient used Uber as his means of transportation.
On 10/23, around 10:15AM, the patient first reported a fever. At this point, the patient called Medecins Sans Frontieres and the New York City Health Department. He was immediately taken to Bellevue by FDNY EMS. The patient was tested for Ebola at the Health Department’s Public Health Lab. Test results are presumptive positive for Ebola. A confirmatory test will be conducted by the CDC; results will be available within the next 24 hours.
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....Don't do it Fred, no upside there, asking the wife would be all risk no reward.
OK, you convinced me.
how coarse and distateful. the proper term is did she guzzle his custard.
... Belch his seed.
Once the prostitutes get it, that is the END. Their married clients will not fess up until they are vomiting blood.
I noticed that the number treated at Emory University didn't equate to what the public has been told when an anonymous patient was releasted. Lends creedence to the claim that patients are disappearing somewhere. Along with the war on Hazmat suits ( so as not to scare) we're not even allowed accurate metadata about how many are being treated. And on another note, Pham was on the tele like frigging Santa Claus on christmas eve. So much for HIPPA.
EBOLA – CIA Project Codename MKNAOMI & Hi-Tech Assassinations
In 1948, Henry Kissinger, a 23-year-old American intelligence officer, recruited Nazi expatriates to serve in top positions in American military, aerospace, and biological science and medicine. Twenty years later, he left Harvard’s esteemed faculty and resigned a lucrative position as Nelson Rockefeller’s foreign policy attache’ to become President Nixon’s closest advisor and director of the National Security Council. Seeking alternatives to tactical nuclear weapons to bolster America’s “diplomacy” abroad, the paranoid and egomaniacal Kissinger quickly ordered the Army’s Chief of Staff to requisition $10 million from Congress for the development and testing of EBOLA & AIDS-like viruses. Within ten years, the AIDS and Ebola epidemics erupted coincidentally in the regions of Africa ravaged by CIA military covert operations also ordered by Kissinger.
In 1984, Dr. Robert Gallo, of the National Cancer Institute, claimed credit for discovering the AIDS virus. He announced it most likely originated from a monkey virus which spontaneously mutated and naturally jumped species. Dr. Gallo was a biological weapons contractor for the CIA’s top secret “Project: MKNAOMI,” and was paid to produce and test EBOLA, AIDS-like viruses as early as 1970.
EBOLA – CIA Project Codename MKNAOMI & Hi-Tech Assassinations
Damn.
just damn.
What I like is that there is stuff out in the mainstream media talking about how the Russians had to bury some folks accidentally infected in their biological warfare research facilities, but they don't talk about our own biowarfare facilities.
http://www.washingtonpost.com/national/health-science/ebola-crisis-rekin...
I see a scape bear being set up for some shit.
I said it first, here. Prediction.
The plasma therapy is likely to work, I gather.
The antiviral? I'm surprised they had it on hand, maybe the CDC made themselves useful and brought it. But if it worked, he would not be getting worse now. Well, depend on the plasma and good luck.
The anti-viral doesn't need to work on the patient, as long as it works on big pharma's bottom line.
How many surviving patients have received new anti-virals but no plasma?
Brincidofivir has never been tested against RdRp (RNA-Dependent RNA Polymerase) in any published study, let alone peer-reviewed study. The drug brincidofivir is derived from (and is a pro-drug of) cidofivir... To my knowledge, cidofivir was only tested against Measles RdRp, and had an IC50 well in excess of 70uM (results which show cidofivir is poorly active against Measles, a virus in the same Order as Ebola -- Mononegavirales). Apparently brincidofivir could be more useful because it's more bioavailable.
Put another way: The antiviral they are using (brincidofivir) is patented, but has never been tested in animals (murine models nor non-human primate models) against any RNA virus, let alone against Ebola. The only rationale for using brincidofivir is unpublished 'test tube' data from Chimerix showing it is active against Ebola RdRp, but this is data which Chimerix has yet to release in any form.
Now , granted , brincidofivir *could* potentially work against Ebola. But I find it interesting though that only patented therapies are under consideration as treatments, even though off-patent and/or FDA-approved drugs (ie . intravenous cidofivir, oral clomiphene, oral lamivudine, oral amiodarone, etc) may be of use against Ebola at much lower expense and much wider availability.
Operon Labs: US Ebola Death -- Antivirals (Brincidofivir, Cidofivir, and Famipiravir)
http://operonlabs.com/?q=node/16
Jesus, these people have no idea WHAT they're doing...that should be clear already. The "Keystone Cops" thing might be funny if the issue wasn't so serious, and everyone is on their own.
Just want to say, if any of these suited-up jokers comes to your town, stay away from them! Don't let them touch you, or God forbid, enter your home, under any circumstances! If there's some 'medicine' they want you to try, tell them to leave it at the door. Tell them you are self-quarantining, and will gladly provide them with daily temp. information, but they are NOT to enter.
Use your own God-given common sense. Research basic infection control protocols...they aren't THAT complicated, and act in your OWN best interests.
These people will NOT be of any use to you.
Loved that video of the cops throwing potential biohazard waste into a public trash can.
https://www.youtube.com/watch?v=1YZ8zR4inbs
You were not impressed when the second-in-command of the CDC showed up in his white lab coat when Pham was released?
How stupid is the CDC and the USA gov at all levels, to not quarantine someone who has been 'treating' Ebola patients?
No one is that benignly stupid. Guess it's time for the 1% to cull the heard with the help of their political pawns. Gawd.
Spreading 50X faster by air travel than Lancet anticipated: https://www.youtube.com/watch?v=3UxWvRsElZk Also: Obama ordered screening in Africa and on arrival here for all delegates and entourates for the early August African Economic Summit. He also ordered medical tracking for them all, saying it was necessary even if the risk was 'infinitessimal'. One standard for our rulers, another for their slaves.
Anyone read this shit?
Ebola Patient's Fiancee Shares His Altruism
http://www.nytimes.com/2014/10/26/nyregion/new-york-ebola-patients-fianc...
"This week, after learning that Dr. Spencer had brought Ebola home to New York from Guinea, Ms. Dixon also checked herself into the hospital and was put in quarantine as a precaution. She returned home Saturday evening and will continue her quarantine there.
Ms. Dixon appeared to take the initial news with grace.
“She literally was like, ‘This is amazing, being in a privileged position in a well-resourced country,’ ” said a longtime friend, Shalva Wise, who said she spoke to Ms. Dixon by phone on Friday afternoon. “She was also thinking about the folks over there who he left behind.”"
Ebola. We amazed some folks. We'll altruise some folks
And we get to put "Medicines Sans Frontiers" on our resume!
I bugged out 13 years ago. What the fuck is everyone waiting for?
Can we please get an update black and white photo of the alleged victim. Or is he like TED who had only 1 picture in his green jacket?
Nope... You'll get the Osama, Davey Jones, "night time burial" version, and like it.
Perfect. On the day he was supposedly killed Osama got more frequent flyer miles that I get in a year. And no photos of the burial at sea service, even where every sailor on the ship has a cell phone?
I thought there was a three week incumabtion period?
Why would they not want to keep the fiance for that timeframe?
Incubation period is a lognormal or Poisson distribution that looks like the link below... I agree, it's surprising to me that they are releasing many of these patients relatively early into the recovery period where they could shed virus in fluids like breast milk, semen, etc.
Ebola Incubation Period Probability Distribution -- per CDC
http://www.cdc.gov/mmwr/preview/mmwrhtml/figures/su6303a1appendixf4.gif
Also, the serial interval in the 2014 outbreak is longer than the serial interval measured in previous Ebola outbreaks. This suggests there may be certain 'differences' in compartment durations. I don't think it's wise to make presumptions about the Ebola 2014 virus, which is poorly studied and poorly understood... Even Ebola itself is poorly understood. We don't even have crystal structures for all of the viral proteins yet. I think it'd be wise for public health officials err on the side of caution.
I do not know why they have not given this doctor tekmiras drug. It has cured every one it has been given to, I believe it is available. All I ever hear about from the msm is zmapp which is 5 for 7. It has to be a political thing.
There are a significant number of off-patent recently-discovered therapies that work against Ebola in animal models. I could make a very large list of such drugs -- many of which are already FDA-approved and were not intended to treat Ebola, but work via novel off-target mechanisms of action. Some have protective efficacy up to 90% or more.
Part of what's going on here is the preferential use of experimental patented drugs (ie. brincidofivir) vs experimental non-patented drugs (ie. clomiphene). Not sure the reason for the preferential use of patented therapies, but it may have to do with the fact that it is easier to find funding for tests in murine and NHP models for drugs which are still covered by patents. . . On the other and, I don't understand this because brincidofivir has never even been tested in animals... If that's the route we are taking, why are we excluding cheaper , more widely available alternatives for in vivo 'right to try' testing in humans (ie. clomiphene, lamivudine, which are cheap and widely available in any pharmacy etc).
Heck, even brincidofivir is simply an ester pro-drug which is significantly more bioavailable version of the off-patent drug cidofivir. Both have the same active metabolite -- 'cidofivir DP'. The other thing that bothers me is that the data on the experimental Ebola clinical protocols are being kept secret and are not being published for review and evaluation.
operon, thanks for taking the time to post this analysis.
You don't get ebola from having sex with an infected person. You have to be infected by a CIA agent or by a contaminated vaccine.. That's my take on it.
He is receiving "Plasma Therapy"
A friend of mine just went through this for an condition unrelated to ebola.
The cost? Medicare pays around $6000 for one treatment. Multipe treatments may be used.
Plus hospital costs etc. ...
Fine for one guy, but multiply times big X? Totally unsustainable.
Anyone who spends 40 minutes in a meatball shop is heading for serious intestinal upsets ...
HomObbama unleashed Homo$sexual marriage & Drugabuse on the world by their legalization.
One sccrewws from bottom and another from top. What is left of the inbetween.
Due the immorality unleasehed , no more family values , no father, no mother, no brother, no sister, no daugther , no son ...
Only pleasure of the carnal type - This is what Obbama gives you , the ruler of the world.
So nature unleashed Ebola.
"And the Angel poured the cup of tribulations on the mankind" says Revelation, Bible.