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The truly disturbing part is the fact that doctors are prescribing these combinations of medications however some of the combinations are actually rejected or have yet to be authorized by the FDA. Seizures really are a side effect with Contrave and mustn't be taken in people who have seizure disorders. The drug can also raise blood pressure levels and heart rate, and mustn't be used in those with a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise hypertension and pulse rate and must not be used in patients with uncontrolled high blood pressure level, in addition to by a person with heart-related and cerebrovascular (blood vessel dysfunction impacting the brain) disease. 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