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When dealing with weight reduction and the people who go through it you ought to err to the side of caution and let the FDA do its job and demand some investigation be done so your public knows the side effects and risks of the medications before we take them. Keep in mind that drug companies have been in business to generate money and that they would say anything to keep people on his or her medications. Researchers discovered that participants using this drug for the year, lost weight within one month and have kept the body weight off through the 56 weeks from the study. Contrave can be a combination in the drugs naltrexone and bupropion, which generally seems to reflect a fresh trend of weight-loss drugs which can be made up of more than one active ingredient, which may make them more effective and safer. Combo-pilling will be the newest fad or better yet the newest into the future under scrutiny and for that reason it is just more publicly known recently, comb-pilling for weight loss has been around since the eighties. The biggest reason that employing a combination of pills is starting to become popular may be the fact that at the time of right now there aren't long term prescription slimming capsules that have been approved by the FDA apart from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications and some of the combinations have been rejected or have yet to be authorized by the FDA. Seizures are a side effect with Contrave and really should not be taken in people who have seizure disorders. The drug can also raise blood pressure levels and heartrate, and shouldn't be used in those with a history of cardiac arrest or stroke in the earlier six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy using the drug. The FDA also warned that Contrave can raise hypertension and heartrate and must 't be used in patients with uncontrolled high blood pressure, along with by anyone with heart-related and cerebrovascular (circulatory dysfunction impacting mental performance) disease. Patients using a history of heart attack or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes which has a boxed warning to alert medical researchers and patients to the increased risk of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for stop smoking. From a psychiatric viewpoint, evidence suggests that the ordinary neural mechanism for goal-directed behavior has been hijacked with the addiction, and malfunctions so that its ordinary functions are exaggerated and fixated on its object. buy naltrexone in peru . An object generates a stimulus and the person engages in a "goal-directed behavioral response" that generates a "natural high"(Bostwick & Bucci, 2008). 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