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Using two separate drugs to lose weight can be very effective you'll find combinations while watching FDA now awaiting approval. When dealing with weight-loss and the people that go through it you ought to err to the side of caution and allow FDA do its job and demand some research be done so that the public knows the side effects and dangers of the medications before we drive them. Keep in mind that drug companies have been in business to earn money and that they would say everything to keep people on the medications. Researchers found that participants taking this drug for any year, dropped excess weight within four weeks and have kept the weight off through the 56 weeks of the study. Contrave is often a combination from the drugs naltrexone and bupropion, which seems to reflect a fresh trend of weight-loss drugs which can be made up of many active ingredient, which can make them more effective and safer. Combo-pilling may be the newest fad or also the newest to come under scrutiny and thus it is just more publicly known lately, comb-pilling for weight loss has been around since the eighties. The biggest reason that by using a combination of pills is starting to become popular may be the fact that by right now there aren't long term prescription weight loss supplements that have been licensed by the FDA apart from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications although some people might of the combinations are actually rejected or have yet to be approved by the FDA. Seizures really are a side effect with Contrave and mustn't be taken in people who have seizure disorders. The drug can also raise hypertension and heartrate, and mustn't be used in people who have a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise blood pressure levels and heart rate and must stop used in patients with uncontrolled high blood pressure, in addition to by a person with heart-related and cerebrovascular (blood vessel dysfunction impacting the brain) disease. Patients which has a history of heart attack or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. cod naltrexone watson . Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes having a boxed warning to alert health care professionals and patients towards the increased chance of suicidal thoughts and behaviors connected with antidepressant drugs. 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