LIS Technologies' New $6.2M Oak Ridge Building Is The Missing Link In Nano's Fuel-To-Reactor Stack
LIS Technologies just bought the building that makes the Nano Nuclear vertical-integration story look more like a fuel cycle, instead of a slide deck.
The check for $6.2 million purchased K-1580, a 37,803-square-foot, three-story, newly renovated facility at 150 Americus Way on the historic K-25 Enrichment Site of East Tennessee's Technology Park Heritage Center in Oak Ridge, best known as the birth place of the Manhattan Project. It sits next to LIST’s leased K-1330 test-demonstration hall and complements the 206-acre “LIST Island” parcel where the company plans a $1.4 billion commercial laser-enrichment plant.
Jay Yu, Executive Chairman and CEO of LIST as well as Founder and Chairman of the publicly traded Nano Nuclear Energy, called Oak Ridge "the Silicon Valley of Nuclear." For once the geography matches the org chart.
The stack Nano and LIST have been drawing looks like this:
Feedstock → laser enrichment → deconversion → fabrication → reactors → transport → space.
K-1580 is where the middle of that chain is supposed to live.
Christo Liebenberg, LIST president and co-founder, said the building will host a pilot plant for the company’s SMILE program (Stable and Medical Isotope Laser Enrichment), office space for more than 100 additional employees, industrialization of critical laser-enrichment components, and a UF6 deconversion pilot.
COO Lloyd Jollay was more specific about why deconversion is the point:
“The facility also offers dedicated laboratory space for investigating UF6 deconversion processes. Integrating deconversion capabilities with uranium enrichment will create a more comprehensive fuel cycle solution and address key needs expressed by a number of advanced reactor developers.”
Those reactor developers are not hypothetical, they sit in the same building.
Nano’s lineup is KRONOS (stationary high-temperature gas-cooled MMR, now in NRC construction-permit territory via the University of Illinois deployment), ZEUS (solid-core battery reactor), and LOKI (portable, being prepped for space). Nano bought Kronos and Loki out of Ultra Safe Nuclear’s bankruptcy at the end of 2024, then hired Ameresco to engineer them toward commercialization. The fuel those machines need is LEU for the existing US fleet and HALEU for the SMRs. That is exactly what LIST’s CRISLA-3G laser process is being built to make.
The two companies already have the contract language. Nano invested in LIST in 2024 with an enriched-uranium supply agreement. Under the collaboration, Nano is supposed to develop the upstream capabilities to feed LIST UF6, then take LIST’s enriched UF6 into an integrated fuel-manufacturing process so the same molecules can land in Nano’s cores, or be sold into the wider industry. Nano is also a key subcontractor on LIST’s DOE award: LIST was one of six names on the up-to-$3.4 billion LEU Enrichment Acquisition IDIQ, with Nano bringing the licensing and advanced-reactor paperwork. They are related parties through overlapping ownership and officers. Yu is the overlap that matters.
Put K-1580 into that map and the campus reads left-to-right:
- K-1330 (leased demo) - LIST’s test loop. Tennessee already issued a radioactive-material license so they can bring in UF6 and run the laser. NRC engagement for classified-handling procedures is underway on the demo.
- K-1580 (just bought) - SMILE medical/stable isotopes, UF6 deconversion pilot, Phase II enrichment in a prototypical environment, component manufacturing, 100 desks. The deconversion step is what turns enriched hexafluoride into something a fabricator, or a KRONOS, can actually use.
- LIST Island (206 acres, former Duct Island) - the commercial LEU-3 / Project F.U.E.L. hall. Groundbreaking still targeted for 2026, subject to licensing, permitting, and a final investment decision. Commercial operations still “before 2030.”
- Nano’s other pillars - fuel fabrication (still the stated intent, no site announced), Secured Transportation Services for moving the material, and NANO Nuclear Space, which wants ZEUS and LOKI in cis-lunar power and eventually propulsion.
Medical isotopes are not a distraction in this narrative. Hospitals need precursor stable and enriched isotopes; quantum and advanced electronics want the same separation physics. SMILE lets the laser earn its keep on non-weapons-grade product while the uranium line walks up the TRL ladder. LIST says CRISLA-3G is at TRL-4, about 75% of the way to TRL-5, and moving toward TRL-6. Phase 2 of the pilot is still the gate before anyone should pretend they have commercial enrichment economics. That is their language, not ours.
What this week’s check actually does is nail a street address onto the middle of the stack. Enrichment at K-1330, deconversion and isotopes at K-1580, commercial plant on LIST Island, reactors at Nano, logistics at STS, space at NNS. One chairman, one Oak Ridge campus, and a fuel molecule that is supposed to never leave the family.
Whether the NRC, DOE, and the fabricator that does not yet have a building cooperate is the next chapter, but at least the org chart is no longer the bottleneck. The physical campus is starting to look like the chart.

